The amniotic membrane is one of the promising cells widely used in eye surgery and the treatment of corneal diseases. The amniotic membrane transplant is a surgical treatment for diseases of the eye surface such as chronic ulcers or dry eyes. The composition of the amniotic membrane is similar in structure to that of the conjunctiva. For this reason, it improves support for stem cells and corneal cells. It excludes inflammatory cells and limits the formation of scars.
- People with inflammatory corneal diseases
- Individuals with dry eye or corneal ulcer
Between 30 and 60 minutes
- 86 %
What is an amniotic membrane?
The amniotic membrane is a translucent vascular tissue derived from the placenta. It is separated under strict aseptic conditions immediately after delivery and treated in a tissue bank approved by the health authorities.
It can be present through cryopreserved leaves, which can be rooted into the eye after thawing, or in the form of freeze-dried powder, which can be used as eye drops after preparation under aseptic conditions. It can also appear in the form of a freeze-dried leaf intended for direct implantation in the eye.
Furthermore, the donation of the amniotic membrane remains voluntary and anonymous. It is suggested to pregnant women whose birth is cesarean. A single membrane could serve up to 30 eye dressings.
The amniotic membrane tissue is perfect for epithelial growth. It is known for its anti-angiogenic, anti-inflammatory, and antibacterial properties. It helps in the healing of lesions. The amniotic membrane is used to grow cells in the laboratory as a framework for tissue engineering.
Amniotic membrane transplant
The amniotic membrane transplant is performed as a complement to another treatment of the surface of the eye (cornea or conjunctiva):
Cornea: the transparent anterior part covering the front of the eye
- Conjunctiva: the transparent layer of cells that covers the cornea and the underside of the eyelids.
Performed on the damage of the cornea or conjunctiva, the amniotic membrane operates as a dressing. It thus releases the substances that constitute it and makes it possible to:
- Restore damaged tissue
- Relieve inflammation and pain
- Keep the eye from rubbing eyelids.
- In case of holes or ulcers on the cornea, it also helps to fill the tissue lapses.
The amniotic membrane is used with ocular stem cells to restore the formation of corneal cells and to save vision in cases that have had severe burns, edema, or ulcers on the surface of the eye.
The process of amniotic membrane transplantation in Istanbul Turkey
The amniotic membrane transplant will take place in the best clinics in Istanbul Turkey. Depending on the patient, ocular surgeons apply local anesthesia or even both general anesthesia if necessary.
Before the intervention
It is necessary to:
- Report to your ophthalmologist: if you have a current or recent infection
- Inform your ocular surgeon about current treatments, allergies, etc.
On the day of the intervention
When you arrive at the clinics in Istanbul Turkey, a nurse will take you to the operating room. Indeed, it positions you on an operating table under a microscope while covering your head with a sterile sheet. In the case of local anesthesia, drops are applied to the eye.
Usually, this surgery lasts between 30 and 60 minutes during which you will be aware and feel no pain.
During the intervention
Your eyelids will be opened with a retractor, which expresses the swelling of the eye after the operation. First, ocular surgeons in Turkey eliminate damaged tissue from your eye. Then, the sterile amniotic membrane is applied to the damaged area and set up using biological glue or stitches.
After the intervention
When you get back from the OR, you are in a room. The medical team in Turkey tells you when you can eat and drink. Generally, following a local anesthetic, you can feed yourself as soon as you arrive in your room.
A few hours after the procedure, a doctor assesses the condition of your eye and authorizes your exit. The nurse puts drops of eye drops in your eye, to prevent any possible infections or inflammations.
Depending on your type of intervention, other treatments will be appropriate (prescription, eye drops, appointments, and post-operative recommendations) especially for the first few days following the intervention (protective lens, eye protection, etc.).
Remember, you need to follow monitoring consultations.
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